wharfe
 
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Genetically modified crop sites in Britain 
Clicking on a site on the map will identify the first instance of a test site.  
Others may exist; check the list for details. 
 
Applicant Organism Purpose Release Date Release Sites
 
1998 Applications
Monsanto Life Sciences Crop Protection
PO Box 53 Lane End Road, High Wycombe Buckinghamshire, HP12 4HL 
Sugar Beet, modified with gene CP4 EPSPS to overcome the effects of glyphosate, which is the active ingredient of the broad spectrum herbicide Roundup Bioactive. Trials designed to complement a world wide programme to provide an alternative and more environmentally benign method of weed control in beet crops.  March to May in the Spring, and September to January of the following year, 1998 to 2003  field 1 Brooms Barn Experimental Station, Higham, Suffolk 
 
field 2 Agrisearch, Wilson, Derbyshire 
 
field 3 Garendon Park Farms, Loughborough, Leics 
 
 Monsanto Life Sciences Crop Protection
PO Box 53 Lane End Road High Wycombe, HP12 4HL 
Sugar Beet, modified with gene CP4 EPSPS to overcome the effects of glyphosate, which is the active ingredient of the broad spectrum herbicide Roundup Bioactive.  Trials designed to complement a world wide programme to provide an alternative and more environmentally benign method of weed control in beet crops.  March to May in the Spring, and September to January of the following year, 1998 to 2003  field 1 Brooms Barn Experimental Station, Higham, Suffolk 
 
field 2 Wood Farm, Morley Research Station, Attleborough, Norfolk 
 
Monsanto Life Sciences Crop Protection
PO Box 53 Lane end Road High Wycombe, HP12 4HL 
Sugar Beet, modified with gene CP4 EPSPS to overcome the effects of glyphosate, which is the active ingredient of the broad spectrum herbicide Roundup Bioactive.  Designed to complement a world wide programme to provide an alternative and more environmentally benign method of weed control in beet crops.  March to May in the Spring, and September to January of the following year, 1998 to 2003. Additional release during August to October (terminated Feb-April) and March to April 
(terminated July/August). 
 
field 1 Brooms Barn Experimental Station, Higham, Suffolk 
 
field 2 Wood Farm, Morley Research Station, Attleborough, Norfolk 
 
field 3 NIAB Huntingdon Road, Cambridge 
 
field 4 Crown Point Estate, Kirby Bedon, Norwich 
 
field 5 Brunsted Hall, Stalham, Norfolk 
 
field 6 Church Farm, Hardley, Norwich 
 
Monsanto Life Sciences, Crop Protection
PO Box 53, Lane End Road, High Wycombe Buckinghamshire, HP12 4HL 

Consent not yet issued as at 8th April 1998

Oilseed rape modified to overcome the effects of glyphosate.  To evaluate the selectivity and efficacy of applications of Roundup Bioactive, in which glyphosphate is the active ingredient, on Oilseed rape.  August to October and July to September 1998-2003, and some trials in the Spring (March- May) which will also be terminated between July and September. 
 
field 1: Twenty Pence Road, Cottenham, Cambridge 

field 2: Lodge Farm, Kings Newton, Derbyshire 
 

Sharpes International Seeds Ltd. 
Plant Breeding Station Boothby Graffoe Lincoln, LN5 0LF 
Sugar beet hybrids, 
modified to produce tolerance to the non-selective herbicide glufosinate ammonium. Modification includes gene coding for neomycin phosphotransferase (nptII) and confers resistance to kanamycin. The nptII gene originated from transposon Tn5. Herbicide tolerance is conferred by the pat gene which is fused to the Cauliflower Mosaic virus (CaMV) 35S promoter and the 35S polyadenalyation signal from CaMV. 
 
To evaluate the level of tolerance to glufosinate and agronomic performance of the genetically modified sugar beet in field trials  Plants sown February to May 1998 and harvested during September to December. Work is part of a 10yr program ending in 2007.  field 1 Sharpes International Seeds Ltd, Plant Breeding Station, Boothby Graffoe Lincoln, LN5 0LF 
 
Nickerson BIOCEM Ltd 200 Science Park Cambridge CB4 4GZ 

Consent not yet issued as at 8th April 1998

Oilseed rape modified using 
Agrobacterium tumefaciens 
mediated transformation of 
cotyledonary explants. The 
method used was essentially that of Moloney et al. (Plant Cell Reports 8, 238-242, 1989) which used a disarmed 
strain of Agrobacterium. The gene of interest is included on a modified Ti plasmid along with the selectable marker gene. A small number of plants have additionally two selectable marker genes conferring resistance to the 
antibiotics ampicillin and gentamycin. These genes are not expressed in the plant. 
 
Small scale field trial to test the introduced genes under field conditions and to bulk up seed for future releases. Plants have been modified - 1) pod shatter reduction genes - reduction of pod 
shatter to reduce the amount of seed lost at harvest. 2) oil modification genes - to alter the composition of fatty acids present in the seed, with the aim of increasing the range of uses for rapeseed oil. 
One year release to be planted after the 1st March 1998 and harvested at maturity (before 31st October 1998)  field 1 Sacrewell Lodge farm, Thornhaugh, near Peterborough 
Scottish Crop Research Institute 
Invergowrie Dundee DD2 5DA Scotland, UK 

Consent not yet issued as at 8th April 1998

Potato modified by the insertion in sense or antisense orientation of genes involved in starch or sugar metabolism or inplant growth regulations.  to produce tubers to determine nutritional values such as glycoalkaloid, chlorogenic acid, vitamin C, protein, starch and sugar content and protein, starch sugar quality and fry colours. 
Secondary purpose is to produce field grown (seed) tubers for subsequent trialling of clones in coming years. 
 
late April/early May to September/October in 1998, 1999, and 2000  field 1 Blythbank farm, nr W.Linton, Peebleshire 

field 2 Gourdie Farm, nr Invergowrie, Dundee 

Nickerson BIOCEM Ltd 200 Science Park Cambridge CB4 4GZ 
 
 
Oilseed rape modified using Agrobacterium tumefaciens 
mediated transformation of 
cotyledonary explants. The method used was essentially 
that of Moloney et al. (Plant Cell Reports 8: 238-242, 1989) which used a disarmed strain of Agrobacterium. The gene of interest is included on a 
modified Ti plasmid along with the selectable marker 
gene. A small number of plants have additionally two 
selectable marker genes conferring resistance to the 
antibiotics ampicillin and  gentamycin. These genes are not expressed in the plant. 
 
Small scale field trial to test the introduced genes under field conditions and to bulk up seed for future releases. Plants have been modified - 1) pod shatter reduction genes - reduction of pod shatter to reduce the amount of seed lost at harvest. 2) oil modification genes - to alter the composition of fatty acids present in the seed, with the aim of increasing the range of uses for rapeseed oil.  One year release to be planted after the 1st March 1998 and harvested at maturity (before 31st October 1998)   field 1: Sacrewell Lodge farm, Thornhaugh, near Peterborough 
John Innes Centre 
Norwich Research Park Colney Norwich NR4 7UH 
Spring barley, variation Golden Promise, containing genes for improvement of malting quality derived from Aspergillus. Plants also contain a bar gene derived from Streptomyces which 
confers resistance against the herbicides containing phosphinothricin/ glufosinate as an active ingredient. The reporter genes used in the transcript are either the uid gene from E.coli which gives a visible blue product, or the luc gene from firefly which causes a release of light when it cleaves the substrate luciferin. Transcript also contains a bla gene which encodes ampicillin resistance, but as this 
is controlled by a bacterial promoter it is not expressed in the plants. 
 
three year programme to test the effect of the introduced genes on malting quality eg the proportion of starch in the barley endosperm that is converted to sugars, and the agronomic performance 
of the transgenic plants (flowering time, plant height, grain yield and its components). 
March to September for three years (1998-2000)  John Innes Centre, Norwich Research Park Colney Norwich, NR4 7UH Norfolk 
CPB Twyford Ltd 
Church Street Triplow Royston Herts SG8 7RE 

Consent not yet issued as at 8th April 1998

Genetically modified plants comprising a hybrid variety of oilseed rape and a male sterile line used to produce the hybrid. Each are modified by the insertion of the pat (Phosphinothricin 
Acetyl Transferase) gene which expresses tolerance to phosphinothricin (the alternative older chemical name for glufosinate, the active principle of the total herbicide glufosinate ammonium). The pat 
genewas originally discovered in the bacterium Streptomyces viridochromogenes isolated from a soil sample from Cameroon but is now produced synthetically. The regulatory DNA used to control expression of the glufosinate tolerance is derived from cauliflower mosaic virus. 
 
To enter the variety for official testing under MAFF to obtain National List status.  August 1998 to August 2001 
 
 Site 1 NIAB HQ Trialground, Huntingdon Road, Cambridge, Cambridgeshire 
 
Site 2 ADAS Boxworth, Boxworth, Cambridgeshire 
Zeneca Limited
Jealotts Hill Research Station, Bracknell, Berkshire, RG42 6ET. 

Consent not yet issued as at 8th April 1998

Oilseed rape, breeding line Westar, modified by introduction of a gene from either Dahlia merckii or Alium cepa to confer anti-microbial properties and addition of the bacterial npt II gene 
(from E.coli) to confer resistance to the antibiotic kanamycin. 
 
To assess the potential impact of transgenic plants expressing anti-microbial proteins on soil microorganisms.  From 1 June 1998 To 30 September 1998  The trial site is at Jealotts Hill Research Station, near Bracknell, Berkshire. 
 
The public website from which this information was obtained is only updated to 8th April 1998. 
More information will be added as it becomes available.
 
Applicant Organism Purpose Release Date Release Sites
 
1997 Applications
AgrEvo UK Crop Protection Ltd, East Winch Hall, East Winch, King's Lynn, Norfolk, PE32 1HN 
 
 
 
 
Sugar beet modified by the insertion of pat (Phosphinothricin Acetyl Transferase) gene to express tolerance to phosphinothricin (the alternative older chemical name for glufosinate, the active principle of the total herbicide glufosinate- ammonium) and nptll neomycin phosphot\ ransferase) gene to express resistance to the anti-biotic kanamycin . The pat gene is a synthetic construct and the 
regulatory sequences are derived from the cauliflower mosaic virus and the bacterium Agrobacterium tumefaciens. 
To enable residue, efficiency, variety performance and variety registration studies to be conducted to support the development of the herbicide glufosinate- ammonium as a selective herbicide Sowing March/ April with harvesting in October/ November or December of each year (1997/2001)  Site 1: Gravel Pit Farm, Exening, Newmarket, Suffolk, Further details of the remaining sites in 1997 and the following 4 years will be provided as soon as they are available. (sic)
Sharpes International Seeds Ltd,  
Plant Breeding Station, Boothby Graffoe, Lincoln LN5 0LF 
 
Sugar beet modified to be tolerant to the herbicide glufosinate ammonium by the insertion of the pat gene. The npt II marker gene for kanamycin resistance is also present. 
 
To evaluate the level of tolerance and agronomic performance of the genetically modified sugar beet hybrid under various herbicide treatments.  10 year programme of work, from 01 March 1997 to 31 December 2006 1997 site: address as above. In later years additional sites may be used 
Sharpes International Seeds Ltd,  
Plant Breeding Station, Boothby Graffoe, Lincoln LN5 0LF 
 
 
Roundup resistance of Spring Oilseed Rape To evaluate Roundup Resistance in Spring Oilseed Rape and conduct National List Trials for variety registration and similar trials.  From 01 February 1997 to 31 October 2006  1997 sites: 
1. NL: Cambridge:TBA: TBA; 

2. NL: Aberdeen: Links Hill Farm, Udny, Aberdeenshire, Scotland:[NG 903 227]; 

3. NL DUS plots: Cambridge: NIAB HQ Trialground, 
Huntingdon Road, Cambridge: [TL 4327 6025]; 

4. HGCA: Edinburgh: Boghall Farm, BiggerRoad, Penicuik, Mid-Lothian: [NT 253 649]; 

5. BSPB: Nickersons: ClaxbyGrange Farm, Market Rasen, 
Lincs. LN8 3YP: [TF 010 963]; 

6. BSPB: Dalgety: Throws Farm, Stebbing, Great Dunmow, Essex, CM6 3AQ: [TL 667 229]; 

7. BSPB: Perryfields: Perryfields Holdings Ltd, Thorn Farm, Inkberrow, 
Worcs, WR7 4LJ. 

1998 sites to be determined (sic) 
 

AgrEvo UK Crop Protection Ltd,  
East Winch Hall, East Winch, King's Lynn, Norfolk, PE32 1HN 
 they are confirmed. 
Oilseed rape modified by the insertion of pat gene (Phosphinothricin acetyl Transferase) to express resistance to glufosinate- ammonium and resistance to kanamycin (marker gene). The pat 
gene is a synthetic construct and the regulatory sequences are derived from the cauliflower mosaic virus. 
 
Field Release of  Glufosinate Ammonium Tolerant Spring Oilseed Rape for Demonstration and Research and Development Purposes  From 01 March 1997 to 31 August 1998  Site 1: Experimental Farm, AgrEvo UK Crop Protection Limited, East Winch Hall, East Winch, King's Lynn, Norfolk PE2 1HN [National Grid Reference TF705163]. 

Further sites will be 
notified when they are confirmed. (sic)

Plant Genetic Systems NV
Nazarethse Steenweg 77, B-9800 Astene (Deinze), Belgium 
Oilseed rape modified to tolerate glufosinate- ammonium herbicide and for male sterility and fertility restorer functions  To verify the stability of the nuclear male sterility/restored fertility system under specific environmental conditions, through agronomic evaluation of 3 male sterile lines, 3 homozygous restorer lines m 9 combinations (between male sterile and restorer lines) and Reference varieties. From 01 March 1997 to 31 October 2001  Site 4401: Melbourn, Cambridgeshire; Grid Reference: TL 3290 427; 

Site 4402: Louth, Lincolnshire; Grid Reference TF 305 893; 

Site 4403: ADAS High Mowthorpe; Grid Reference: SE 894 690; 

Site 4404: SAC, Craibstone, Aberdeen; Grid Reference NJ 876114 
 

CPB Twyford Ltd,  
Church Street, Thriplow, Royston, Herts SG8 7RE 
Oilseed rape modified to contain the kanamycin resistance gene and with resistance to kanamycin. Laurate canola differs from its parent in the fatty acid composition of the seed; the fatty acid laurate is much more abundant in the GMPts. The gene of interest codes for 12:0 ACP thioesterase. The thioesterase enzyme causes laurate to accumulate (by cleaving lauroyl-ACP) instead of being converted to longer chain fatty acids. 
 
To continue to evaluate and select a range of rapeseed lines modified with Calgene's gene for high lauric acid oil alongside conventional rapeseed cultivars for agronomic performance and oil quality. Assessment of the material is with a view to future commercial production and for the continuation of a plant breeding programme. The trial series is planned to continue initially over a three year period and to involve spring adapted lines of oilseed rape. 
 
From 01 March 1997 to 30 September 1999  Site 1 (spring sowing 1997) Perrins Field, Thriplow, Royston, Herts [National Grid Reference: TL 432475]. 

Further details of the 2 sites scheduled for 1998 and the 2 sites for 1999 will 
be made available at a later date (sic)

Plant Genetic Systems NV,  
Nazarethse Steenweg 77, B-9800 Astene (Deinze), Belgium 
 
Oilseed rape modified to tolerate glufosinate-ammonium herbicide and for male sterility and fertility restorer functions  In the frame of the official variety registration of PGS' hybrid oilseed rape it is intended to carry out official DUS (Distinctiveness- Uniformity-Stability) trials in the United Kingdom. DUS trials comprise a number of different tests over a minimum two year test period in order to identify and characterise a line. DUS Alternatively testing aims to evaluate the behaviour of spring oilseed rape types under winter conditions 
 
From 1 March 1997 to 28 February 1998  National Institute of Agricultural Botany HQ, Huntingdon Road, Cambridge 
John Innes Centre, Norwich Research Park, Colney, Norwich NR4 7UH 
 
Spring wheat containing genes for improvement of baking quality. Genes have been inserted to improve dough elasticity. In addition, the plants carry a gene for glufosinate herbicide resistance and the gusA gene (for glucuronidase) as a marker, and the bacterial bla gene conferring resistance against ampicillin. 
 
A 3 year programme to test the agronomic performance of the transgenic wheat plants and to increase seed for biochemical evaluation.  From 01 March 1997 to 31 August 1999  address as above 
Monsanto Plc, 
Crop Protection, PO Box 53, Lane End Road, High Wycombe, Buckinghamshire HP12 4HL 
 
Spring oilseed rape modified with Roundup Ready genes (glyphosate tolerance)  The proposed experimental programme is based on progeny of spring oilseed rape plants containing the Roundup Ready genes (tolerance to glyphosate). The general purpose of this 
experimental programme is to assess the performance of Roundup Biactive applications to control the weeds in a spring oilseed rape crop and generate the necessary data for the registration of this Roundup Biactive use. There will also be small scale plots in order for the technology to be demonstrated to selected groups. 
From 1 March 1997 to 30 September 2001  Throws Farm 
Brocklesby, 
N. Lincs, 

Manor Farm Worsley, Stebbing Wilton 
Great Dunmow 
Essex 

Herbicide Registration trials: 

Firtree Farm Lodge Farm, Ibstock 

Grange Farm Fillongley Kings Newton Pretoria Road Nr. Coventry Derbyshire; 

Tib Hall Farm, Kingsbury, Nr. Tamworth, Staffordshire SP 228933 
 

AgrEvo UK Crop Protection Ltd,  
East Winch Hall, East Winch, King's Lynn, Norfolk, PE32 1HN 
 
Maize modified by the insertion of pat gene (phosphinothricin acetyl transferase) to express tolerance to glufosinate, the active principle of the total herbicide glufosinate-ammonium and the ampR  (ampicillin resistance) gene to express resistance to the -lactam antibiotics in bacteria only. This latter gene is incomplete or disrupted and is thus inactive and is also not expressible in the plant. 
 
To enable efficacy and demonstration work to be conducted with the herbicide glufosinate- ammonium.  From 1 April 1997 to 30 November 1998  Site 1: East Winch Hall, East Winch, King's Lynn, Norfolk PE32 1HN. National Grid Reference TF 705163. 

Further sites will be notified when they are confirmed. 

Plant Genetic Systems NV, 
Jozef Plateaustraat 22, B-9000 Gent, Belgium 
 
Oilseed rape modified for male sterility with tolerance to Phosphinothricin and reduced susceptibility to fungal infection  The release aims to evaluate the general agronomic performance, in particular the tolerance to fungal infections in several hybrids in comparison to some check varieties. From 01 August 1997 to 30 September 2001.  The field test will be located on Craibstone Estate, 5 miles west of Aberdeen, by the Aberdeen to Inverness road (A96). Grid Ref NJ 873 112. 
 
AgrEvo UK Crop Protection Limited, 
East Winch Hall, East Winch, King's Lynn, Norfolk PE32 1HN 
Winter oilseed rape modified to express either glyphosate tolerance or glufosinate ammonium tolerance.  Field release of oilseed rape tolerant to two different herbicides to investigate the consequence of outcrossing between the two lines. To produce seed with tolerance to both 
herbicides and to investigate the susceptibility of these plants to other herbicides.
From 01 August 1997 To 30 September 1999  Site1: Experimental farm, AgrEvo UK Crop Protection Limited, East Winch Hall, East Winch, King's Lynn, Norfolk PE32 1HN. National Grid Reference: TF 705163 

Site 2: Chishill Orchard Farm, Heydon Road, Great Chishill, Royston Wider, Herts SG8 8SS. National Grid Reference: TL429393 
 

CPB Twyford Ltd,  
Church Street, Thriplow, Royston, Herts SG8 7RE 
The GM Winter Oilseed Rape contains the kanamycin resistance gene from Tn5, and is resistant to kanamycin. Laurate canola differs from its parent in the fatty acid composition of the seed: the fatty acid laurate is much more abundant in the GMO.  To continue to evaluate and select a range of rape seed lines modified with Calgene's gene for high lauric acid oil alongside conventional rape seed cultivars for agronomic 
performance and oil quality. Assessment of the material is with a view to future commercial production and for the continuation of a plant breeding programme. The trial series is planned to continue initially over a three year period and to involve winter adapted lines of oilseed rape. 
 
From 01 August 1997 To 31 August 2000 Site 1 (autumn sowing 1997): Camps field, Newton, Royston, Herts National Grid Reference: TL 444 491. Further sites in 1998 and 1999 will be notified when 
they are confirmed. 
AgrEvo UK Limited,  
East Winch Hall, East Winch, King's Lynn, Norfolk, E32 1HN 
Insertion of genetic material; 35 S promoter and terminator from CaMV (cauliflower mosaics virus), pat (phoshinothricin acetyl-transferase) gene originally from 
Streptomyces viridochromogenes (now synthetic). 
 
For demonstration and research and development.  From 01 August 1997 To 30 September 1999  Site 1: Experimental farm: AgrEvo UK Limited, East Winch Hall, East Winch, King's Lynn, Norfolk PE32 1HN, National Grid Reference: TF 705163
Plant Genetic Systems NV,  
Nazarethse Steenweg 77, B-9800 Astene (Deinze), BELGIUM. 

Organism: 
Purpose: 

Release Dates: 

Release Sites : 
 

Oilseed rape modified to express tolerence to phosphinothricin herbicide and male sterility and restorer functions. 
 
To verify the stability of the male sterility/restorer fertility system under specific environmental conditions. Also to evaluate the agronomic performance of transgenic hybrids and evaluate resistance to light leaf spot (Pyrenopeziza brassicae).  From 1 August 1997 to 31 August 1998  Site 4401, Melbourn: The field site will be located on arable land at Summerhouse Farm in Melbourn, Cambridgeshire. Grid Ref: TL396 424. 

Site 4402: Aberdeen The field test site will be located on Craibstone Estate, Bucksburn, 5 miles west of Aberdeen. Grid Ref: NJ 873 112. 

Site 4403: High Mowthorpe The field test site will be located at ADAS High Mowthorpe, Lincolnshire (sic). Grid ref: 883 697. The nearest village is Kirkby Grindalythe. 

Site 4404: Cirencester The field test site will be located on Dryleaze Farm, Siddington, Ciorencester, Gloucestershire. Grid Ref: SU 033 976. 

Site 4405: Dartford. The field test site will be located on South Darenth Farms and Coldstores Ltd, St Margareths Farm, South Darenth, Dartford, Kent.Field number 0540. 
 

The Scottish Agricultural College,  
Craibstone Estate, Bucksburn, Aberdeen AB21 9YA. 
 
Oilseed rape modified to contain the kanamycin resistance gene from Tn5 and express resistance to kanamycin. Laurate canola differs from its parent in the fatty acid composition of the seed;. the fatty acid laurate is present in the GMO unlike conventional oilseed rape.The gene of interest codes for 12.0 ACP thioesterase. The thioesterase enzyme causes laurate to accumulate (by cleaving 
lauroyl-ACP) instead of being converted to longer chain fatty acids. 
 
A comparison of the potential of oilseed rape of differing fatty acid profiles (including high lauric rape (Brassica napus) to produce volunteer populations.  From 01 October 1997 to 01 October 2000  Woodlands Field, Craibstone Estate, Bucksburn, Aberdeen, AB21 9YA 
John K King & Sons Ltd, Coggeshall, Colchester, Essex CO6 1TH 
 
Oilseed rape (laurate canola) genetically modified to contain the kanamycin resistance gene from Tn5, and to be resistant to kanamycin. Laurate canola differs from its parent in the fatty acid 
composition of the seed; the fatty acid laurate is present in the GMO unlike conventional oilseed rape. Research in the UK suggests that laurate rapeseed is less persistent as a volunteer than 
conventional high oleic varieties. Observations made in trials over the last 5 seasons in the UK indicate that the GMO is not more weedy, persistent, invasive or prolific than currently grown canola 
varieties, and the GMO exhibits no selective or competitive advantage. 
 
To evaluate high lauric rapeseed (Brassica napus) for National List Trial (NLT) purposes.  From 1 March 1998 to mid November 2003.  Field 1: NIAB, Huntingdon Road, Cambridge CB3 0LE 

Field 2: SAC, Tillycorthie, Udny, Aberdeenshire AB41 6SD 

 IACR - Rothamsted, Harpenden, Hertfordshire AL5 2JQ 
 
Spring wheat (Triticum aestivum), resistance to herbicide phoshinothricin + inserted GUS maker gene  To assess the field performance of the transgenic plants and to produce sufficient amounts of grain for detailed analysis of processing properties Growing season, March - August (1998 - 2001)  Site 1: IACR-Long Ashton Research Station, Long Ashton, Bristol BS18 9AF 

Site 2: IACR- Rothamsted, Harpenden, Hertfordshire AL5 2JQ 

Site 3: Haverholme, near Sleaford, Lincolnshire 
 

 John K King & Sons Ltd Coggeshall, Colchester, Essex, CO6 1TH.  Oilseed rape modified to contain the kanamycin resistance gene from Tn5, and is resistant to kanamycin. Laurate canola differs from its parent in the fatty acid composition of the seed; the fatty acid laurate is present in the GMO unlike conventional oilseed rape. The gene of interest codes for 12:0 ACP thioesterase. The thioesterase enzyme causes laurate to accumulate (by cleaving lauroyl-ACP) instead of being converted to longer chain fatty acids. The parent does not possess this enzyme but produces thioesterases (with significant sequence homology to the 12:0 thioesterase) that act on longer fatty acid chains. Use of the napin promoter restricts the fatty acid modification to the developing seed. Laurate canola consistently has greater levels of Laurate in seed than do canola varieties, which is the main criteria used to assess activity of the 12:0 ACP thioesterase enzyme in the GMO. 
 
The industrial evaluation of high lauric rapeseed (Brassica napus) grown under commercial conditions in the UK.  From 1 March 1998 to 1 November 2000  Field 1: Whitehouse, Newcastle, Monmouthshire NP5 4NF. Other fields (approx 14 sites) - details to be provided later.
Sharpes International Seeds Ltd.  
Plant Breeding Station Boothby Graffoe Lincoln, LN5 0LF 
Sugar beet hybrids, modified to produce tolerance to the non-selective herbicide glufosinate ammonium. Modification includes gene coding for neomycin phosphotransferase (nptII) and confers resistance to kanamycin. The nptII gene originated from transposon Tn5. Herbicide tolerance is conferred by the pat gene which is fused to the Cauliflower Mosaic virus (CaMV) 35S promoter and the 35S polyadenalyation signal from CaMV. 
 
To evaluate the level of tolerance to glufosinate and agronomic performance of the genetically modified sugar beet in field trials  Plants sown February to May 1998 and harvested during September to December. Work is part of a 10yr program ending in 2007.  field 1 Sharpes International Seeds Ltd, Plant Breeding Station, Boothby Graffoe Lincoln, LN5 0LF 
Novartis Seeds Ltd, Brooke Lodge, Brooke, Norwich, NR15 1JG 
 
Sugar beet (Beta vulgaris) transformed with Agrobacterium tumefaciens, conferring tolerance to glufosinate- ammonium by the introduction of the PAT gene. Promoter and terminator of cauliflower mosaic virus (35-sRNA gene) also introduced. 
 
To test tolerance to the herbicide glufosinate- ammonium of sugar beet, with the long term aim to develop commercial sugar beet varieties to provide farmers with an alternative weed management system in combination with glufosinate-ammonium.  Spring/Summer 1998 - Autumn/Winter 2002 field 1 Hill Farm, Kirby Bedon, Norwich, Norfolk 
Plant Genetic Systems NV,  
Jozef Plateaustraat 22, B-9000 Gent. Belgium 
 
Oilseed rape modified for male sterility and restored fertility, with insertion of genetic material by (Agrobacterium tumefaciens mediated) transformation.  DUS (Distinctiveness- Uniformity-Stability) trials comprise a number of different tests over a minimum two year test period in order to identify and characterise a line. DUS alternatively testing aims to evaluate the behaviour of Spring oilseed rape types under Winter conditions. 
VCU (Value- Cultivation-Use) trials and recommended trials are set up in order to evaluate the agronomical value of crop varieties. The trials are carried out on a national basis and take a minimum of 2 years for addition to the UK National and recommended list. 
 
From 1 March 1998 to 28 February 1999  The trials will be located at NIAB Headquarters, Huntingdon Road, CB3 0LE, Cambridge. The trials will be conducted on 10 to 15 locations max. Full descriptions on the locations of the 
release sites will be notified as soon as this information becomes available.
Pioneer Genetic SARL Technical and Regulatory Affairs, Chemin de l'Enseigure, Postbox 6 31840 Aussonne, FRANCE 
 
 
 
Spring oilseed rape (Brassica napus) variation Westar containing Roundup ready genes. These genes contain 
(1) an EPSPS gene from Agrobacterium CP4 codes for modified EPSPS enzyme. The EPSPS enzyme is naturally occurring in plants and is the target for glyphosphate herbicide. The CP4 EPSPS enzyme 
is insensitive to glyphosphate. 
(2) a gene sequence coding for a chloroplast transit peptide from Arabidopsis thaliana 
(3) a gene sequence derived from Achromobacter coding for the glyphosphate oxido-reductase enzyme active in glyphosphate metabolism in the plant, fused to the chloroplast transit peptide sequence 
from A.thaliana. 
 
To test the agronomic performances of modified spring oilseed rape tolerant to glyphosphate with the aim of obtaining National Listing  March - September 1998  (1) NIAB Huntingdon Road, Cambridge CB3 0LE 

(2) SAC Tillycorthie Udny, Aberdeenshire AB41 6SD 

(3) NIAB Headquarters, White House Lane, Cambridge CB3 0LE 

(4) SAC Bohall Farm, Bigger Road, Penicuik, Mid-Lothian 

(5) Balby Farms Ltd, Brigsley, Lincolnshire 

(6) Throws Farm, Stebbing, Great Dunmow, Essex CM6 3AQ 

(7) NIAB site 15miles from Inkberrow, Worcestershire 

 
Applicant Organism Purpose Release Date Release Sites
 
1996 Applications
Monsanto Plc,  
Crop Business Unit, PO Box 53, Lane End Road, High Wycombe, Buckinghamshire HP12 4HL 
Sugar Beet, modified with Roundup Ready genes  Evaluation of agronomic and biological characteristics of a beet crop transformed to be tolerant to Roundup and assessing the performance of Roundup in controlling A three year programme from March 1996 to December 1998  Mere Hall, Bracebridge Heath, Lincoln; 

Honeyhill Farm, Saxham, Bury St. Edmunds; 

Garendon Park Farms. Ashby Road, Loughborough; 

Didbrook Fields, Toddington, near Cheltenham 
 

Scottish Crop Research Institute,  
Invergowrie, Dundee DD2 5DA 
 
Potatoes, modified for altered carbohydrate metabolism and the marker genes for resistance to kanamycin and hygromycin 
 
To produce tubers for chemical analyses and fry testing and for seed for further trials  October 1996 - October 1998 Gourdie/Mylnefield Farm, near Dundee
Scottish Crop Research Institute,  
Invergowrie, Dundee DD2 5DA 
1. Potatoes (Catriona, Desiree, Pentland Crown, Pentland Squire) with the GUS gene from E.coli with CaMV promoter; 

2. the cDNA of the SAMDC gene of potato with the HPTII gene which expresses hygromycin resistance; 
 
3. potatoes transformed with a plasmid containing a tetracycline repressor ; 
 
4. the rol C gene of Agrobacterium rhizogenes under the control; 
 
5. the potato leafroll virus coatprotein gene (PLRVcp). 

In all the above (except (ii)) the NPTII kanamycin resistance gene is present 
 

To produce tubers for destructive analyses post storage to determine nutritional value in comparison with non- transformed equivalents and to produce seed tubers for subsequent trialling of 
clones in coming years. 
 
April 1996 - October 1998  Gourdie/Mylnefield Farm, near Dundee
Advanced Technologies (Cambridge) Limited  
210 Cambridge Science Park, Cambridge CB4 4WA 
 
Potatoes (Record, Desiree, Prairie & Hermes) modified to alter sugar and starch metabolism. To test the commercial potential of the modified varieties  April 1996 - November 2001  Crifton Lodge Farm, Hexgreave Farm, Bilsthorpe 

Lord's Ground Farm, Swaffam Prior, Burwell 
 

Monsanto Plc,  
Crop Protection, PO Box 53, Lane End Road, High Wycombe, Buckinghamshire HP12 4HL 
 
Sugar Beet, modified with Roundup Ready genes  Evaluation of agronomic and biological characteristics of a beet crop transformed to be tolerant to Roundup and assessing the performance of Roundup in controlling weeds in a beet crop. 
 
A five year programme from March 1996 to December 2000 Auborn Farming, Auborn, Lincoln 
 
AgrEvo UK Crop Protection Ltd,  
East Winch Hall, East Winch, King's Lynn, Norfolk PE32 1HN 
 
Potatoes (Desiree) modified by the insertion of marker genes for resistance to kanamycin or hygromycin and the coding region of various genes for starch metabolism 
 
To investigate the biosynthesis of starch; the physical, chemical and biochemical analysis of modified starch and to identify breeding lines of particular use  Four year programme of work from April 1996 - September 1999  address as above
Plant Breeding International Cambridge Limited,  
Maris Lane, Trumpington, Cambridge CB22LQ 
 
Potatoes (Desiree) modified to express altered carbohydrate metabolism and the marker genes for resistance to kanamycin and hygromycin 
 
To multiply transgenic potato lines which have been shown in glasshouse tests to contain modified starch May 1996 - November 2001  address as above 
Nickerson BIOCEM Ltd,  
200 Science Park, Milton Road, Cambridge CB24RL 
 
The plants to be released are high erucic acid spring oilseed rape plants which have been modified using Agrobacterium tumefaciens mediated transformation to insert the 
1acyl-sn-glycerol- 3-phosphate acyl transferase gene from Limnathes douglassi to alter the fatty acid composition of the oil. This gene is under the control of a seed specific promoter from oilseed rape 
(napin), which means that the gene is only expressed in the seed. Also present in these plants is a selectable marker gene, kanamycin resistance, under the control of a 35S promoter which is expressed 
throughout the plant. 
 
- Planting in March, April or May depending on weather conditions and availability of seed. In 1996, when the consent is granted. Harvesting will take place at maturity, which we anticipate will be no later than the end of October in any year for the duration four year of the programme of work. The final release in the programme will terminate by the end of October 1999.  Nickerson Seeds Ltd, Woolpit Business Park, Woolpit, Bury St Edmunds, Suffolk IP30 3UP, Grid Reference: 9662 
Perryfields Holdings Ltd, Thorn Farm, Inkberrow, Worcs. WR7 4LJ 

 

Winter oilseed rape modified for tolerance to glufosinate ammonium herbicides.  To conduct a two year variety registration programme.  Sowing August 1996/7, harvesting 30 September 1997/8  1996/7: 
Manor Farm, Caxton, Cambs; 

ADAS Bridgets, Martyr Worthy, Winchester, Hants; 

Edge House Farm, Belsay, Newcastle upon Tyne; 

Tillycorthie Farm, Udny Station, 
Aberdeenshire; 

Highfield, Dennington Road, Framlingham, Woodbridge, Suffolk; 

Manor Farm, Twyford, Banbury, Oxon; 

Cotehill Farm, Osgodby, Market Rasen, Lincs; 

Two sites at NIAB HQ trial ground, Huntingdon Road, Cambridge; 

ADAS Boxworth, Boxworth, Cambs; 

Wood Farm, Runhall, Norwich, Norfolk; 

Bollington Hall Farm, Ugley, Essex; 

Bramham Farm Partnerships, Terrylug Farm, Bramham, Wetherby; 

Bank Farm, Bank Lane, Aldington, Ashford, Kent; 

West Craigie Farm, South Queensbury, Lothian. 
(recte South Queensferry) 

Sites will be notified for 1997/8 in due course 
 

Monsanto Plc,  
Crop Business Unit, PO Box 53, Lane End Road, High Wycombe, Buckinghamshire HP12 4HL 
 
Winter oilseed rape modified for tolerance to glyphosate herbicides 
 
To conduct a variety registration programme. To assess the performance of glyphosate herbicide applications to control the weeds in a winter oilseed rape crop and generate the necessary data for the registration of this Roundup use.  Sowing August 1996/7/8, harvesting July1997/8/9  1996/7: 

Two sites at NIAB trial ground, Huntingdon Road, Cambridge; 

NIAB trial site, Martyr Worthy, Winchester; 

Manor Farm, Caxton, Cambridge; 

Edge House Farm, Belsay, 
NrPonteland, Newcastle upon Tyne; 

Tillycorthie Farm, Udny Station, Aberdeen 

Highfield, Framlingham, Woodbridge, Suffolk; 

Manor Farm, Twyford, Banbury, Oxon; 

Cotehill Farm, Osgodby, Market Rasen, Lincs; 

ADAS Boxworth, Boxworth, Cambridge; 

Morley EHF, Wood Farm, Runhall, Nr Wymondham, Norfolk; 

Bollington Hall Farm, Ugley, Essex; 

Bramham Farm Partnerships, Terrylug Farm, Bramham, Wetherby; 

Wye Agric College, Bank Lane, Aldington, Nr Ashford, Kent; 

West Craigie Farm, South Queensbury, Lothian. 
(recte South Queensferry) 

Sites will be notified for 1997/8 and 1998/9 in due course 
 

Zeneca Limited,  
Jealott's Hill Research Station, Bracknell, Berks RG42 6ET 
 
Poplar (Populus tremula x Populus alba) genetically modified by the addition of one of the following: antisense cinnamyl alcohol dehydrogenase (CAD) or antisense O-methyl transferase (OMT). Both contain the marker gene npt II conferring kanamycin resistance. Both antisense genes alter the phenotypic expression of lignin and are coupled to the 35 S promoter from Cauliflower Mosaic Virus and the nos terminator from Agrobacterium tumefacien. 
 
Assessment of agronomic and pulping characteristics of poplar genetically modified to alter lignin composition  December 1997 to December 2004  address as above 
Hilleshog (UK) Ltd, Brooke Lodge, Brooke, Norwich NR15 1JG 
 
Sugar beet genetically modified for tolerance to the herbicide Roundup, with GUS marker gene  The proposed experiments are part of a mid- to long-term breeding programme based on progeny of sugar beet plants containing the Roundup Ready genes (tolerance to glyphosate). The aim of the programme is to develop commercial sugar beet varieties which can be used in combination with Roundup to provide the farmers with an alternative weed management system.   From 01 March 1997 to 30 November 2001  The application is for a programme of work that will extend over 5 years from 1997 to 2001. There will be in the region of 9 sites in year 1 (1997) and in the region of 21 sites in subsequent years, all will be in England but the exact number may vary from year to year. The detailed locations can only be provided in late winter/early spring of each trialing year when NIAB's trialing plans have been completed. However one site which can be noted to be definitely used in all 5 years of the programme applied for is: The Exning Estate company Exning Estate Office Exning, Newmarket Suffolk CB8 7NN. 
 
Monsanto Plc,  
Crop Protection, PO Box 53, Lane End Road, High Wycombe, Buckinghamshire HP12 4HL 
 
Sugar Beet, modified with Roundup Ready genes (glyphosate tolerance)  The proposed release is part of a programme to develop Beta vulgaris plants containing the Roundup Ready genes (which confer tolerance to the herbicide glyphosate). The aim of this programme is to provide farmers with an alternative weed management system for the sugar beet crop. 
 
 From 01 March 1997 to 31 January 2000  Broom Barn Experimental Station, AFRC Institute of Arable Crops Research, Higham, Bury St Edmunds, Suffolk IP28 6NP, [National Grid Ref: TL752656] 
 
Applicant Organism Purpose Release Date Release Sites
 
1995 Applications
Bejo Zaden BV,  
Trambaan 1, 1749 ZH Warmenhuizen, Netherlands 
 
Chicory, modified for male sterility and resistance to gluphosinate ammonium & neomycin phosphotransferase. 
 
Test of agronomic performance of transgenic hybrids   June - November, 1995 - 2000 Elsoms Seeds Ltd trial field, Pinchbeck Marsh, Spalding, Lincolnshire
Zeneca Limited,  
Jealott's Hill Research Station, Bracknell, Berks RG126EY 
 
Poplar, with cinnamyl alcohol dehydrogenase antisense & o-methyl transferase antisense genes. 
 
To compare agronomic aspects & pulping characteristics with unmodified poplar  April 1995 - December 2002  address as above 
Plant Breeding International Cambridge Limited,  
Maris Lane, Trumpington, Cambridge CB2 2LQ 
 
Potatoes (Maris Bard, Maris Piper, & Desiree varieties) with shrub, barley or potato virus genes 
 
To produce seed tubers for further experimental work  April - October, 1995-98  PBI farm, Contrannie, Nr Bankfoot, Perthshire
Plant Breeding International Cambridge Limited,  
Maris Lane, Trumpington, Cambridge CB2 2LQ 
 
Potatoes, with genes coding for non-toxic protein giving resistance to potato cyst nematodes, & kanamycin resistance To assess field performance of the nematode resistant plants April -October, 1995-98  1) address as above 

2) ADAS, Arthur Rickwood Experimental Husbandry Farm, Mepal (near Ely), Cambridgeshire (from 1996) 
 

Scottish Crop Research Institute,  
Invergowrie, Dundee DD2 5DA 
 
Strawberry containing the Cowpea trypsin inhibitor  To determine if the CpTi gene inserted into strawberry confers resistance to strawberry weevil 
 
September 1995 - September 1998 East Pilmore Holding, Tayside, Scotland 
Sharpes International Seeds Ltd,  
Sleaford, Lincolnshire 
 
Brassica napus L (swedes or fodder or oilseed rape)with Roundup resistance, transformed using established Agrobacterium technology, Also contains marker genes. 
 
To evaluate the GMO's agronomically and academically, particularly to test their resistance to Roundup  The application is for a 10 year programme 1995-2005, with the first release scheduled for February/March 1996  Boothby Graffoe, Lincoln and Mylnefield, Invergowrie, Dundee
Sharpes International Seeds Ltd,  
Plant Breeding Station, Boothby Graffoe, Lincoln LN5 0LF 
 
Sugar beet expressing a fructosyl transferase gene and producing small amounts of high molecular mass fructan, with GUS and Kanamycin resistant marker genes 
 
To evaluate the agronomic performance of fructan producing sugar beet 
 
A ten year programme of work planned to run from 1996 - 2005  Plant Breeding Station, Boothby Graffoe, Lincoln and IACR, Brooms Barn, Higham, Bury St. Edmunds, Suffolk
Hilleshog NK,  
Brooke Lodge, Brooke, Norwich NR15 1JG 
 
2 lines of sugar beet, transformed with Agrobacterium tumefaciens using standard techniques 
 
To test the tolerance to the herbicide Roundup of sugar beet progeny, containing the Roundup Ready genes 
 
Programme of work initially covering five years from Spring 1996 to Winter 2000  Kirby Bedon, Norwich and Stalham, Norfolk 
Nickerson BIOCEM Ltd, 200 Science Park, Milton Road, Cambridge CB44GZ 
 
Potatoes genetically modified for altered carbohydrate composition in the tubers with marker genes expressing kanamycin resistance and GUS 
 
To test the field performance of the inserted carbohydrate modification genes  Four year programme of work from June 1996 - October 1999  Pitgaveny Estate, Elgin, Morayshire
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Pitgavenny Estate, ElginUdny, Aberdeenshire Craibstone, AberdeenBucksburnContrannie, Nr BankfootInvergowrie, Dundee DundeePenicuik, Mid-LothianWest Linton, PeebleshireBelsay, nr PontelandHigh MowthorpeBramham, WetherbyOsgodby, Market RasenBrigsley, LincolnshireMarket Rasen, Lincs.Louth, LincolnshireBilsthorpeAuborn, LincolnBracebridge Heath, LincolnBoothby Graffoe, LincolnHaverholme, near SleafordPinchbeck Marsh, SpaldingThornhaugh, near PeterboroughWilson, Derbyshire  Wilson, DerbyshireIbstockLoughboroughKings Newton, DerbyshireLong Ashton, Bristol   Newcastle, MonmouthshireSiddington, CirencesterKingsbury, nr. TamworthThorn Farm, InkberrowToddington, nr CheltenhamTwyford, BanburyMartyr Worthy, WinchesterBracknell, BerkshireHarpenden, HertfordshireEast Winch, King's LynnStalham, NorfolkHardley, NorwichKirby Bedon, NorwichFramlingham, WoodbridgeAttleborough, Norfolk Colney, NorwichRunhall, NorwichHigham, Bury St EdmundsWoolpit, Bury St EdmundsSouth Darenth, DartfordAldington, nr AshfordGreat Chishill, Royston WiderStebbing, Great DunmowUgley, EssexThriplow, RoystonMelbourn, CambridgeshireNewton, RoystonTwyford, BanburyExning, NewmarketSaxham, Bury St. EdmundsBoxworth, CambridgeshireCambridgeCottenham, CambridgeCaxton, Cambs.